ALGAE BIOMASS RESEARCH LABORATORY
Algae Biomass Research Laboratory is an Industry supported research lab established under the Department of Biotechnology, School of Agriculture and Biosciences with a vision to“Research on micro and macroalgae”.Ongoing algae research addresses the issues on water, energy, environment and health, as micro and macro algae are known to perform photosynthesis and produce half of the atmospheric oxygen, while using simultaneously the greenhouse gas carbon dioxide to grow photo-autotrophically and reduce carbon foot print. Microalgae produce unique products like carotenoids, antioxidants, fattyacids,enzymes,polymers,peptidesandtoxins and hence find wide applications.
Algae Biomass Research Laboratory
The research lab particularly focuses on biotechnology based production of value added products by means of cost effective and energy efficient process. Projects by DST-SERB,DBT and UGC enhanced the capacity of the lab by adding sophisticated equipment that cater to the R&D initiatives and train research scholars, undergraduate and postgraduate students and IAESTE interns. The lab is equipped with instruments like Algae Growth Chamber, Thermalcycler (PCR), and Microscope with documentation systems and deep freezer to carry out research work in the interdisciplinary areas of algal biotechnology.
ANIMAL TISSUE CULTURE LAB
Animal Tissue Culture Lab
Animal and human cell culture methods lead to breakthrough in medical Biotechnology, including the production of vaccine, recombinant proteins, monoclonal antibodies (mAbs), and cells for transplantation. Cell culture techniques, which involve culturing nucleated (eukaryotic) cells under prescribed conditions within the laboratory, provide ample opportunities for students to have hands on training in maintenance and preservation of cell lines, cytotoxicity analysis and genotoxic assays. The Cell culture laboratory is designed for the maintenance, preservation and observation of cells. This laboratory enables students to gain knowledge in vitro culturing of animal cells, passaging and cryopreservation of cells, nuclear staining, cytotoxicity and enzyme assays.
Bioprocess Lab focus on frontier areas for conversion of biological materials into valuable forms for mankind. Applications associated with bioprocess engineering includes design and operation of fermentation systems, development of biological products and processing systems, product separation technologies, design of instrumentation to monitor and control biological processes and production of biofuels. Students are trained in the application aspects through problem solving techniques. Projects done in the lab bridge the gap between the bench top research lab and the large-scale implementation of bioprocess in food and pharmaceutical production systems.
The Biosafety facility established belongs to the BSL Class-II category and houses a BSL 2B Biosafety Cabinet with a virus burnout attachment. This facility provides researcher to work on moderate risk pathogens such as Influenza virus, Hepatitis virus, Hog Cholera Virus, Rabies virus bacteria such as Aeromonas, Mycobacterium leprae, Haemophilus, Klebsiella, Closterdium tetani, Enterobactrial species and fungi such as Candida, Cryptococus and also parasites such as Ascaris, Entamoeba, Plasmodium, Taenia solium, Trypanosoma etc
The genomics facility recently established is one of the lab focusing on cutting edge technologies. The Real time quantification DNA and RNA during its amplification is a technology used in detection of the desired nucleic acids with applications in food, health care and environmental issues. The lab helps students and scholars in monitoring and quantifying gene expression for clinical diagnosis such as cytokine profiling, cancer, diagnosis of infectious agents especially viruses and also in the assessment of viral load which helps in determining antiviral treatment.
CELL BIOLOGY LAB
Cell Biology Lab
The cells are seen through the eye of the microscope and thereafter the interactions of the antigen and the antibody are best demonstrated via the Cell Biology and Immunology Lab. The nature and the morphology of the cells which also include blood cells, cells of the spleen and the other vital organs are visualized. The students at this facility learn blood types and their grouping. This laboratory plays a pivotal role in enhancing the skill which a student has to acquire when learning the cellular and immunological interactions of the human and the animal system which also paves a way to be part of Biopharmaceutical industry.
DOWNSTREAM PROCESSING LAB
The Downstream processing Lab focus on the technologies and strategies developed for recovery and purification of various bio-products based on microbial cultures/ plant cells/ animal cells. The laboratory is dedicated to train the students on various unit operations involved in downstream processing. The major facilities include bench top fermenters, extractors, homogenizers, centrifuges, spectrophotometer, and incubator shaker.
Downstream Processing Lab
FUNDED RESEARCH LAB
Funded Research Lab
Department has received funding for research from various national and international funding agencies like DRDO, ICSSR, TNSCST, DBT, ICMR, DST-SERB, BESI, NTRF and UBCHE at the tune of 2 crores. New facilities have been created with sophisticated equipment funded by Government agencies to undertake research in frontier areas. The faculty members have national as well as international collaborations to leverage the scientific advantage and develop mutually beneficial scientific interactions. The lab remains open to pursue and promote world-class research and training at the frontiers of cancer therapeutics, Water treatment technologies, algal research, phytotherapeutics and microbial resistance studies. The outcome of the project can be either converted into scientific publications, products and patents.
BIOINFORMATICS RESEARCH LAB
Welcome to the Bioinformatics lab at Department of Biotechnology KITS. We develop and apply in silico tools that apply computational chemistry, molecular modeling, and theoretical systems biology to simulate molecular and cellular processes. The sophisticated lab facilitys are utilized for academic and research purpose the studies includes lab studies the mechanisms by which transcription factors are recruited to their specific DNA sites, both in vitro and in vivo, and how this recruitment is affected by changes in the DNA or protein sequence. We use protein binding microarray assays and computational approaches that combine different types of information relevant for DNA binding and transcriptional regulation.
Bio Informatics Research Lab
HIGH PERFORMING COMPUTING LAB
High Performance Computing Lab
The High Performance Computing Laboratory at KITS, Department of biotech Conducts research in several areas with IBM BioCluster server machine works on optimizing compilers, performance modeling and optimization, parallel algorithms, and software engineering. Example projects include static and dynamic analysis of software for building application performance models, ensuring software quality, or detecting security vulnerabilities; using machine learning and other approaches to model run-time characteristics of software; developing data mining techniques to study and improve HPC software engineering processes; applying natural language processing methods to study and improve HPC software developer productivity; designing new algorithms or improving existing ones in several application areas, including large-scale dynamic graphs, computational physics, and computational biology.
This laboratory helps students to gain knowledge on the clinical role of biomolecules in biological samples and understand their importance in the cells and organs of the body using advanced analytical techniques.
The Research laboratory provides infrastructure for Ph.D. scholars to work on their priority/chosen areas of biotechnology and their allied fields using the state-of- the- art equipment. The laboratory facilitates the scholars to conduct cutting-edge research in the frontier areas of biotechnology leading to the development of product/process/prototype focusing on the vision and mission of the Institute. The laboratory research focuses on areas like cancer biology, microbiology, biochemistry, plant and animal biotechnology, bioprocess and environmental.
MOLECULAR BIOLOGY LAB
Molecular Biology and Genetic Engineering lab provides a platform for basic molecular biology techniques in isolation and quantification of DNA, RNA and Proteins. Equipped with PCR, apparatus for electrophoresis, Gel documentation system and other accessory equipment, the lab has been the source of good quality research papers. This facility is also being employed for training Undergraduate and Post graduate students in molecular biology and genetic engineering and get them prepared to face the biotech industry.
Molecular Biology Lab
PG RESEARCH LAB
PG Research Lab
PG Research Lab in the department of Biotechnology provides necessary working areas, with basic instrumental facilities to carry out day to day research activities. Apart from routine pH meter, Colorimeter, autoclaves, shaker incubator, HEPA laminar airflow system, we have sophisticated instruments like Thermo-fisher scientific RT-PCR, and NanoDrop Spectrophotometer. Thermo-fisher scientific RT-PCR is used to determine the expression level of target genes in biomedical science research including SARS-CoV, immunological response, Cancer management and nanotoxicology studies for semiquantitative analysis. Thermo fisher scientific NanoDrop Spectrophotometer specifically for the measurement of nucleic acid concentrations using small sample volumes as little as one microliter. Refrigerated Remi centrifuge for downstream processing. Deep freezer (-40°C) supports storage of culture, and consumables. Bioanalytical analytical instruments such as Lab-Man UV-visible Spectrophotometer and Gen5 Microplate reader support determination of absorbance at specific wavelength/ wavelength for various assays like MTT assay, MIC.
PLANT TISSUE CULTURE LAB
Plant tissue culture and cell culture technologies are used for micro propagation, genetic improvement and conservation of genetic resources of endangered plants and in vitro production of plant metabolites of medical significance. Students are given ample opportunities to have hands-on training on in vitro propagation techniques like induction of callus, shoot, root, plant transformation techniques and cell culture techniques for biomass production of secondary metabolites. The research focus of this laboratory is to propagate endangered and commercially important medicinal plants and to produce plant metabolites through cell culture technologies which enable the students to improve their technical skills in plant tissue culture technology and product development.
Plant Tissue Culture Lab
Microbiology laboratory provides academic, research & training, and consultancy services. Various experiments on staining, culturing, enumeration and biochemical characterization are designed to cater the requirements of the curriculum and the same is nurtured to the students through practice. In this laboratory, both Under Graduate and Post Graduate students carry out their respective or assigned experiments to accomplish their academic credits. In addition, the students can perform a wide range of experiments in the areas of bacteriology, mycology, parasitology etc. The laboratory is equipped with instruments and lab benches to implement practical based learning among the students.